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Health > Physical Health > Weight Management

Clinical Study: This African Fruit Can Boost GLP-1 by Over 50%

Clinical Study: This African Fruit Can Boost GLP-1 by Over 50%

New research reveals how a rare African fruit naturally increases the same hormone that Ozempic sells and why it can save you from putting on 21 pounds of fat.

Words by

Niki Geary

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Published on: Apr 29, 2025

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If you're a woman in your 40s or 50s, this might sound familiar:


You're doing everything right, the same habits that kept you fit for decades. Morning walks. Carefully portioned meals. No eating after 7 PM.


Yet the scale keeps climbing, becoming especially visible around your midsection. And those cravings that are unlike anything you've experienced before.


You're not imagining it. You're not failing. And you're definitely not alone.


There's a scientific reason why your body seems to be working against you during menopause...


So don't go anywhere, I will shortly break it down and show you the at-home fix.

The Hormonal Weight Gain Crisis No One Is Talking About

Recent research has uncovered a startling fact: The average woman gains 8% of their bodyweight in pure fat during the first two years of menopause.


For a regular woman in the US, like myself, this could mean 21 pounds of unnecessary fat gain.


And it doesn't stop there, we continue gaining 1.5 pounds annually through our 50s and 60s.


I will shortly explain why this happens, and how you can prevent it from the comfort of your home without prescriptions, drugs or HRT.


As we all know, during menopause, estrogen levels plummet.


What most health professionals don't explain is that this drop triggers your body to start overproducing an enzyme called DPP-4, what nutritionists are now calling the "skinny hormone killer."


This enzyme has one job: to rapidly destroy GLP-1, your body's natural "skinny hormone" that regulates appetite, cravings, and fat storage.


Even the official GLP-1 Wikipedia page confirms that DPP-4 shuts down over 80% of your natural GLP-1 before it has a chance to do its job

This explains why you might be eating the same foods and doing the same workouts as before, yet watching the numbers on your scale creep up month after month.

The African Fruit That's Changing Everything

In a remarkable twist of scientific discovery, researchers identified an African spice fruit that directly targets this menopausal enzyme with superb results.


A 12-week, placebo-controlled clinical study involving 90 participants confirmed what many scientists had suspected: This African fruit extract, known as Dyglomera®, effectively inhibits the DPP-4 enzyme.


The results were astonishing:


  • The study showed a 59% average reduction in DPP-4 (the "skinny hormone killer")

  • Participants increased their natural GLP-1 levels by an average of 56%

  • Participants experienced significant reductions in appetite and cravings


“This clinical study offers new insights into how these remarkable natural ingredients help individuals achieve and maintain healthy body weight while improving their metabolic health,” said Shil Kothari, President of Gateway Health Alliances...


“Dyglomera may be the first natural ingredient to show direct, measurable and sustainable increases in GLP-1 levels and significant weight loss.”


Dr. Oben remarked, “Our findings are consistent with numerous studies demonstrating the efficacy of Dyglomera in reducing appetite and promoting weight loss… The likely mechanism behind this GLP-1 increase is the inhibition of the enzyme DPP-4.”

"Direct, measurable and sustainable increases in GLP-1 levels and significant weight loss"

Clinical Insights Into a Real-World Solution

Women using MetaGlow™, the only blend in the US that contains the clinically proven dose of Dyglomera®, are reporting remarkable results with real-life insights.


"I've been using metaglow for a little over a month now, and I've noticed a HUGE difference in my appetite, gut health, and energy level, it is amazing compared to other brands that I've used. This will definitely be my new go-to collagen from now on!" Reports Melissa, a verified user.


In customer feedback, women consistently reported three primary benefits:


  • Dramatically reduced cravings, especially for sweets and carbs


  • Consistent energy throughout the day without crashes


  • Reliable, progressive weight management

Beyond the Injections: A Natural GLP Solution

With GLP-1 medications making headlines for their weight loss effects (and their $1,000+ monthly price tags), many women are seeking alternatives without the side effects or expense.


MetaGlow™ takes a fundamentally different approach than these injections. Rather than introducing synthetic hormones, it targets the enzyme that's destroying your body's own natural GLP-1.


"What many people don't realize is that these popular injections don't address the underlying DPP-4 problem that affects menopausal women," notes Michelle Melzl, a Certified Personal Trainer who specializes in women's fitness.


By inhibiting DPP-4, MetaGlow™ allows your body's natural GLP-1 to survive long enough to do its job: controlling appetite, reducing cravings, and signaling your body to burn fat instead of storing it.

Life-Changing Results

The clinical results are impressive, but the personal stories from women whose lives have been transformed are even more powerful:


April K: "I'm 52, in the heat of meno and thought I would give this a whirl. I am wildly impressed! I feel better than I have felt in years adding this to my morning smoothie. My appetite is under control and for the first time in my life my sugar cravings (which were EXTREME) are GONE! Absolutely gone. I just finished my first bag!"


Stephanie H: "I eat healthy, hardly drink and work out regularly yet I have had an extra 10+ pounds that wouldn't budge. Figured I would give it a try since there's a guarantee. I am almost two months in and the biggest win is I have definitely lost weight, my pants are looser. I put it in my coffee each morning."


Ann G: "I added MetaGlow Collagen to my daily wellness routine 2 months ago and I love it. It's right up there with spending time in my garden! Just 1 scoop added to my morning coffee, breakfast shake or coffee has reduced my cravings and bloating."

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Doctor examining a woman's face in a clinic setting.Doctor examining a woman's face in a clinic setting.Doctor examining a woman's face in a clinic setting.Doctor examining a woman's face in a clinic setting.Doctor examining a woman's face in a clinic setting.Doctor examining a woman's face in a clinic setting.Doctor examining a woman's face in a clinic setting.

Read more unfiltered reviews here.

MetaGlow™: The Only US-based African Spice Fruit Formula

After transforming the lives of many women in clinical studies, the GLP-1 boosting powers of African spice fruit is finally available in the US.

Zend Wellness offers an exclusive blend with the clinically tested dose, leaving a remarkable landmark in natural weight management history.

Remember: MetaGlow is backed by a 60-day money-back guarantee. If you aren’t happy with the results, you will get your money back in full, even if the bag is empty.

APPLY DISCOUNT & CHECK AVAILABILITY

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How to Use MetaGlow™ (It Takes Just Seconds)

One of the most appealing aspects of MetaGlow™ is its simplicity.


There's no complicated protocol or restrictive detox diet required.


  • Measure one scoop of MetaGlow™

  • Add it to your morning coffee, tea, smoothie, or oatmeal (or anything else really)

  • That's it! Your natural GLP-1 boost is underway

The powder is tasteless and odorless, dissolving completely without affecting the flavor of your beverage or food...


‘’Although some long-term customers report their coffee becoming a sort of a snack, due to what they describe as a light creamy texture,’’ the company notes.

The Choice Is Yours

Every day your body is fighting the uphill battle against DPP-4 is another day where your natural GLP-1 is being destroyed. Another day where fat storage is winning over fat burning.


The sooner you address this fundamental issue, the easier your weight management journey will be during menopause.


For thousands of women experiencing hormonal weight struggles, MetaGlow™ has provided the missing piece in their health puzzle.


Growing popularity around MetaGlow™ has created supply challenges, the African spice fruit used to produce Dyglomera® is harvested sustainably from specific regions, limiting annual production.


"We're committed to maintaining the highest quality standards, which means we only produce a finite amount at a time," explains the company. "When we sell out, customers may have to wait a few weeks for the next batch."

"When we sell out, customers may have to wait a few weeks for the next batch."

This explains why a lot of women secure multiple months of stock at a time.


Currently, MetaGlow™ is offering special pricing for new customers reading this:


One-time purchase: $59 (20% savings on first purchase with email sign-up)


Monthly subscription: $47/month (20% ongoing savings, shipped free each month)


Three-month subscription: $39/month (34% ongoing savings, shipped free every three months)


All subscriptions are backed by a 60-day risk-free guarantee. You can use the entire bag, and if you don't notice benefits, you'll receive a full refund.

APPLY DISCOUNT & CHECK AVAILABILITY

Remember: Your purchase is protected by a 60-day money-back guarantee. If you aren’t happy with the results, you will get your money back in full, even if the bag is empty.

More Life-Changing Results

The success stories continue to pour in from women over 40:

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Doctor examining a woman's face in a clinic setting.Doctor examining a woman's face in a clinic setting.Doctor examining a woman's face in a clinic setting.Doctor examining a woman's face in a clinic setting.Doctor examining a woman's face in a clinic setting.Doctor examining a woman's face in a clinic setting.Doctor examining a woman's face in a clinic setting.

"I've been using this product for a little over a month now, & l've noticed a HUGE difference in my appetite, gut health, & energy levels."


- Destiny L.

"I was researching products that contained dyglomera and that led me to Zend MetaGlow, so I decided to give it a try. I believe it has helped with appetite suppression, I do feel fuller quicker for sure now and don't snack as much. I also feel a bit leaner generally speaking without modifying anything else. I just started my 3rd bag."


- Amy B.

"I've been using MetaGlow for a couple weeks and am enjoying it and getting results. I definitely notice less hunger, it makes my coffee silky, and I'm glad to find a product that works."


- Paula C.

"I'm in my second month of using this product and have definitely seen my stomach get flatter and have even lost a few pounds. It’s great in my coffee as well as my smoothie."


- Terri A.

"I have been using it for 2 weeks now and I have definitely felt a difference in my cravings for sweets. I am a big sweet nut and that is a big part of my problem, but I managed to really cut back on the cravings thanks to Metaglow."


- Renee B.

Remember: Your purchase is protected by a 60-day money-back guarantee. If you aren’t happy with the results, you will get your money back in full, even if the bag is empty.

APPLY DISCOUNT & CHECK AVAILABILITY

I'm sorry, I can't access URLs or view images directly.

Due to recent media appearances,

stock is limited.


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